gbx2 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-855770

Gene Symbol: gbx2 Gene Name: gastrulation brain homeobox 2, gene 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: gbx2 assayed (2 sources)
Computed annotations: gbx2 assayed (23 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (52 sources): abnormal cerebellar foliation, abnormal cerebellum development, abnormal choroid plexus morphology, abnormal cochlear ganglion morphology, abnormal crista ampullaris morphology, abnormal forebrain development, abnormal fourth pharyngeal arch artery morphology, abnormal hindbrain development, abnormal inferior colliculus morphology, abnormal innervation, abnormal locus ceruleus morphology, abnormal membranous labyrinth morphology, abnormal midbrain development, abnormal midbrain-hindbrain boundary development, abnormal midbrain-hindbrain boundary morphology, abnormal neural crest cell migration, abnormal neural crest cell morphology, abnormal organ of Corti morphology, abnormal pons morphology, abnormal postnatal growth, abnormal rhombomere 5 morphology, abnormal styloid process morphology, abnormal trigeminal ganglion morphology, abnormal vascular endothelial cell differentiation, abnormal vestibular saccular macula morphology, absent cerebellum, absent cochlear ganglion, absent common crus, absent endolymphatic duct, absent lateral semicircular canal, absent posterior semicircular canal, absent scala media, absent superior semicircular canal, absent supraoccipital bone, absent trigeminal nerve, absent vestibular saccule, decreased embryonic neuroepithelial cell proliferation, decreased embryonic neuroepithelium thickness, decreased neural crest cell number, fusion of glossopharyngeal and vagus nerve, increased inferior colliculus size, inner ear cyst, middle ear ossicle hypoplasia, neonatal lethality, complete penetrance, nervous system phenotype, no abnormal phenotype detected, otic capsule hypoplasia, postnatal lethality, incomplete penetrance, preweaning lethality, complete penetrance, retroesophageal right subclavian artery, small otic vesicle, styloid process hypoplasia [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (52 sources): abnormal cerebellar foliation, abnormal cerebellum development, abnormal choroid plexus morphology, abnormal cochlear ganglion morphology, abnormal crista ampullaris morphology, abnormal forebrain development, abnormal fourth pharyngeal arch artery morphology, abnormal hindbrain development, abnormal inferior colliculus morphology, abnormal innervation, [+]