ifnar2.2 Phenotypes

XB-GENEPAGE-855850

Gene Symbol: ifnar2.2 Gene Name: interferon (alpha, beta and omega) receptor 2, gene 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: ifnar2.2 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (15 sources): abnormal CD4-positive, alpha-beta T cell physiology, abnormal cytotoxic T cell physiology, abnormal macrophage physiology, decreased IgG1 level, decreased IgG2a level, decreased interferon-alpha secretion, decreased interferon-beta secretion, decreased interferon-gamma secretion, impaired natural killer cell mediated cytotoxicity, increased incidence of induced tumors, increased incidence of tumors by chemical induction, increased susceptibility to Adenoviridae infection, increased susceptibility to Herpesvirales infection, increased susceptibility to Orthomyxoviridae infection, increased susceptibility to Riboviria infection [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (15 sources): abnormal CD4-positive, alpha-beta T cell physiology, abnormal cytotoxic T cell physiology, abnormal macrophage physiology, decreased IgG1 level, decreased IgG2a level, decreased interferon-alpha secretion, decreased interferon-beta secretion, decreased interferon-gamma secretion, impaired natural killer cell mediated cytotoxicity, increased incidence of induced tumors, [+]