myb Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-867552

Gene Symbol: myb Gene Name: MYB proto-oncogene, transcription factor

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormally decreased number of ionocyte (1 source), abnormally decreased number of non-cililated epidermal cell (1 source), abnormally increased number of multiciliated epidermal cell (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: myb assayed (5 sources)
Computed annotations: myb assayed (13 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + myc-myb (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (55 sources): abnormal T cell differentiation, abnormal angiogenesis, abnormal common lymphocyte progenitor cell morphology, abnormal definitive hematopoiesis, abnormal double-negative T cell morphology, abnormal embryonic erythropoiesis, abnormal erythropoiesis, abnormal hematopoietic stem cell morphology, abnormal hemoglobin content, abnormal liver development, abnormal liver sinusoid morphology, abnormal megakaryocyte differentiation, abnormal megakaryocyte morphology, abnormal myeloblast morphology/development, abnormal seminal vesicle morphology, abnormal single-positive T cell number, absent common myeloid progenitor cells, arrested B cell differentiation, arrested T cell differentiation, decreased B-1 B cell number, decreased CD4-positive, alpha beta T cell number, decreased T cell proliferation, decreased body size, decreased common myeloid progenitor cell number, decreased double-negative T cell number, decreased double-positive T cell number, decreased eosinophil cell number, decreased erythrocyte cell number, decreased gamma-delta T cell number, decreased hematocrit, decreased hematopoietic stem cell number, decreased mature B cell number, decreased pre-B cell number, decreased prepulse inhibition, decreased single-positive T cell number, decreased spleen white pulp amount, decreased thymocyte number, hematopoietic system phenotype, immune system phenotype, increased CD8-positive, alpha-beta T cell number, increased bone marrow cell number, increased double-negative T cell number, increased hematopoietic stem cell number, increased nucleated erythrocyte cell number, increased number of Howell-Jolly bodies, increased spleen red pulp amount, lethality throughout fetal growth and development, complete penetrance, macrocytosis, no abnormal phenotype detected, polychromatophilia, premature death, preweaning lethality, incomplete penetrance, small liver, small spleen, small thymus [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (55 sources): abnormal T cell differentiation, abnormal angiogenesis, abnormal common lymphocyte progenitor cell morphology, abnormal definitive hematopoiesis, abnormal double-negative T cell morphology, abnormal embryonic erythropoiesis, abnormal erythropoiesis, abnormal hematopoietic stem cell morphology, abnormal hemoglobin content, abnormal liver development, [+]