mmp9 Phenotypes

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Phenotypes

Gene Literature (41)

Nucleotides (208)

Interactants (487)

XB-GENEPAGE-876294

Gene Symbol: mmp9 Gene Name: matrix metallopeptidase 9 gene 1

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
decreased cell population proliferation in optic tectum (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: mmp9 assayed (6 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + mmp9 MO (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (13 sources): Abnormal epiphysis morphology, Abnormality of the lower limb, Abnormal metaphysis morphology, Abnormal ulnar metaphysis morphology, Aplasia/Hypoplasia of the radius, Bowing of the legs, Bowing of the long bones, Joint stiffness, Metaphyseal irregularity, Metaphyseal widening, obsolete Abnormality of the ulna, Short femoral neck, Short stature [+]
Mouse (77 sources): abnormal angiogenesis, abnormal blood-brain barrier function, abnormal bone marrow cell physiology, abnormal chemokine level, abnormal circulating aspartate transaminase level, abnormal dendritic cell physiology, abnormal hematopoietic stem cell morphology, abnormal impulse conducting system conduction, abnormal induced retina neovascularization, abnormal intestinal goblet cell morphology, abnormal Langerhans cell physiology, abnormal long bone epiphyseal plate morphology, abnormal long bone hypertrophic chondrocyte zone, abnormal megakaryocyte differentiation, abnormal myocardial fiber physiology, abnormal physiological neovascularization, abnormal response/metabolism to endogenous compounds, abnormal response to cardiac infarction, abnormal response to infection, abnormal retina apoptosis, abnormal tumor morphology, abnormal vascular smooth muscle physiology, abnormal vascular wound healing, cardiac fibrosis, decreased cardiac muscle contractility, decreased circulating aspartate transaminase level, decreased circulating interleukin-10 level, decreased dendritic cell number, decreased histamine level, decreased interferon-gamma secretion, decreased litter size, decreased metastatic potential, decreased myocardial infarct size, decreased neuron apoptosis, decreased oligodendrocyte number, decreased physiological sensitivity to xenobiotic, decreased sensitivity to xenobiotic induced morbidity/mortality, decreased susceptibility to bacterial infection, decreased susceptibility to experimental autoimmune encephalomyelitis, decreased susceptibility to Flaviviridae infection, decreased susceptibility to Flaviviridae infection induced morbidity/mortality, decreased susceptibility to induced arthritis, decreased susceptibility to induced colitis, decreased susceptibility to injury, decreased susceptibility to ischemic brain injury, decreased tumor incidence, delayed bone ossification, delayed wound healing, hypoalgesia, immune system phenotype, impaired contextual conditioning behavior, impaired hematopoiesis, impaired myelopoiesis, increased angiogenesis, increased circulating interferon-beta level, increased circulating interferon-gamma level, increased interferon-gamma secretion, increased interleukin-13 secretion, increased interleukin-4 secretion, increased interleukin-5 secretion, increased macrophage cell number, increased prostaglandin level, increased sensitivity to xenobiotic induced morbidity/mortality, increased susceptibility to dystrophic cardiac calcinosis, increased susceptibility to Picornaviridae infection, increased susceptibility to Picornaviridae infection induced morbidity/mortality, increased susceptibility to type IV hypersensitivity reaction, increased T cell proliferation, increased T-helper 2 cell number, increased tibialis anterior weight, increased vascular permeability, increased ventricle muscle contractility, increased width of hypertrophic chondrocyte zone, reduced fertility, reduced long term potentiation, thick interventricular septum, thick ventricular wall [+]
View all ortholog results at Monarch