abnormal pulmonary alveolus wall morphology, abnormal retina vasculature morphology, abnormal T-helper 1 physiology, abnormal tumor necrosis factor level, acanthosis, decreased cerebral infarct size, decreased circulating interferon-gamma level, decreased circulating interleukin-18 level, decreased circulating interleukin-6 level, decreased energy expenditure, decreased interferon-gamma secretion, decreased oxygen consumption, decreased skeletal muscle weight, decreased spleen weight, decreased susceptibility to bacterial infection, decreased susceptibility to endotoxin shock, decreased tumor necrosis factor secretion, decreased ventricle muscle contractility, dermatitis, excessive scratching, hyperchlorhydria, impaired natural killer cell mediated cytotoxicity, increased circulating histamine level, increased circulating interleukin-18 level, increased circulating tumor necrosis factor level, increased dendritic cell number, increased IgG1 level, increased interferon-gamma secretion, increased interleukin-13 secretion, increased macrophage cell number, increased neutrophil cell number, increased NK cell number, increased percent body fat/body weight, increased right ventricle diastolic pressure, increased right ventricle systolic pressure, increased susceptibility to age related obesity, increased susceptibility to induced colitis, increased susceptibility to parasitic infection, increased total fat pad weight, increased white adipose tissue amount, overexpanded pulmonary alveoli, skin lesions