cxcl12 Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-919852

Gene Symbol: cxcl12 Gene Name: C-X-C motif chemokine ligand 12

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: cxcl12 assayed (22 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (37 sources): abnormal angiogenesis, abnormal blood cell morphology/development, abnormal bone marrow cell physiology, abnormal common lymphocyte progenitor cell morphology, abnormal developmental vascular remodeling, abnormal hematopoietic stem cell morphology, abnormal hematopoietic stem cell physiology, abnormal hematopoietic system morphology/development, abnormal hematopoietic system physiology, abnormal pancreatic islet morphology, abnormal physiological neovascularization, abnormal primordial germ cell migration, abnormal proerythroblast morphology, abnormal vascular smooth muscle morphology, decreased bone marrow cell number, decreased common myeloid progenitor cell number, decreased hematopoietic stem cell number, decreased pre-B cell number, decreased pre-pro B cell number, decreased pro-B cell number, hematopoietic system phenotype, hydrometra, impaired myelopoiesis, increased B cell apoptosis, increased hematopoietic stem cell number, increased neutrophil cell number, lethality throughout fetal growth and development, incomplete penetrance, liver hemorrhage, neonatal lethality, complete penetrance, nervous system phenotype, no abnormal phenotype detected, poor arterial differentiation, premature death, prenatal lethality, complete penetrance, preweaning lethality, complete penetrance, small superior vagus ganglion, thin external granule cell layer [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (37 sources): abnormal angiogenesis, abnormal blood cell morphology/development, abnormal bone marrow cell physiology, abnormal common lymphocyte progenitor cell morphology, abnormal developmental vascular remodeling, abnormal hematopoietic stem cell morphology, abnormal hematopoietic stem cell physiology, abnormal hematopoietic system morphology/development, abnormal hematopoietic system physiology, abnormal pancreatic islet morphology, [+]