intu Phenotypes

XB-GENEPAGE-919871

Gene Symbol: intu Gene Name: inturned planar cell polarity protein

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal cilium assembly (1 source), abnormally decreased number of ciliated cell (1 source), obsolete decreased cilium motility in ciliated epidermal cell (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: intu manipulated (3 sources)
Computed annotations: intu assayed (1 source)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + intu MO (2 sources), Xla Wt + intu MO (1 source), Xla Wt + intu MO (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (32 sources): abnormal cell morphology, abnormal chondrocyte morphology, abnormal cilium morphology, abnormal cranial flexure morphology, abnormal dorsal-ventral axis patterning, abnormal embryonic neuroepithelium primary cilium morphology, abnormal heart looping, abnormal kidney epithelial cell primary cilium morphology, abnormal limb bud morphology, abnormal notochord morphology, abnormal rostral-caudal axis patterning, abnormal spinal cord interneuron morphology, abnormal sternocostal joint morphology, abnormal sternum ossification, absent floor plate, asymmetric sternocostal joints, broad limb buds, decreased birth weight, decreased body size, decreased embryonic cilium length, decreased embryonic cilium number, decreased width of hypertrophic chondrocyte zone, delayed endochondral bone ossification, diencephalon hyperplasia, embryonic lethality during organogenesis, incomplete penetrance, lethality throughout fetal growth and development, complete penetrance, nervous system phenotype, no abnormal phenotype detected, pericardial edema, postnatal lethality, incomplete penetrance, skeleton phenotype, small floor plate [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (32 sources): abnormal cell morphology, abnormal chondrocyte morphology, abnormal cilium morphology, abnormal cranial flexure morphology, abnormal dorsal-ventral axis patterning, abnormal embryonic neuroepithelium primary cilium morphology, abnormal heart looping, abnormal kidney epithelial cell primary cilium morphology, abnormal limb bud morphology, abnormal notochord morphology, [+]