mnx1 Phenotypes

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Phenotypes

Gene Literature (17)

Nucleotides (74)

Interactants (197)

XB-GENEPAGE-919889

Gene Symbol: mnx1 Gene Name: motor neuron and pancreas homeobox 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: mnx1 assayed (9 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (32 sources): Abdominal distention, Abnormal intestine morphology, Anal atresia, Anal fistula, Anal stenosis, Anterior sacral meningocele, Aplasia/Hypoplasia of the sacrum, Arteriovenous malformation, Bicornuate uterus, Bifid sacrum, Bifid scrotum, Chronic constipation, Gastrointestinal obstruction, Global developmental delay, Hemisacrum, Horseshoe kidney, Hypoplasia of penis, Hypospadias, Lower limb asymmetry, Male pseudohermaphroditism, Neurogenic bladder, Perianal abscess, Presacral teratoma, Rectovaginal fistula, Recurrent urinary tract infections, Sacrococcygeal teratoma, Sepsis, Septate vagina, Tethered cord, Urinary incontinence, Vascular dilatation, Vesicoureteral reflux [+]
Mouse (19 sources): abnormal axon guidance, abnormal axon morphology, abnormal duodenum morphology, abnormal innervation, abnormal neuromuscular synapse morphology, abnormal pancreas development, abnormal pancreatic beta cell physiology, abnormal pancreatic delta cell morphology, abnormal pancreatic islet morphology, decreased fetal size, decreased pancreatic delta cell number, decreased skeletal muscle fiber size, immune system phenotype, neonatal lethality, complete penetrance, nervous system phenotype, no abnormal phenotype detected, primary atelectasis, small pancreatic islets, thin diaphragm muscle [+]
View all ortholog results at Monarch