b2m Phenotypes

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Phenotypes

Gene Literature (5)

Nucleotides (306)

Interactants (91)

XB-GENEPAGE-922469

Gene Symbol: b2m Gene Name: beta-2-microglobulin

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: b2m assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (31 sources): Abnormal autonomic nervous system physiology, Autonomic bladder dysfunction, Bowel incontinence, Bronchiectasis, Bronchiolitis, Chronic axonal neuropathy, Chronic constipation, Chronic diarrhea, Chronic otitis media, Chronic sinusitis, Constipation, Decreased circulating IgG level, Ectopia lentis, Emphysema, Gastrointestinal dysmotility, Gastrointestinal hemorrhage, Hypoalbuminemia, Hypoplasia of the ulna, Hypoproteinemia, Intermittent diarrhea, Keratoconjunctivitis sicca, Malabsorption, Nasal polyposis, Orthostatic hypotension due to autonomic dysfunction, Radial bowing, Recurrent bronchitis, Recurrent respiratory infections, Skin ulcer, Vertigo, Weight loss, Xerostomia [+]
Mouse (25 sources): abnormal CD8-positive, alpha-beta cytotoxic T cell morphology, abnormal circulating triglyceride level, abnormal cytotoxic T cell physiology, abnormal embryo size, abnormal interleukin level, abnormal lateral geniculate nucleus morphology, abnormal pancreatic beta cell morphology, abnormal prepulse inhibition, abnormal tumor necrosis factor level, decreased interleukin-4 secretion, decreased level of surface class I molecules, decreased susceptibility to autoimmune diabetes, decreased susceptibility to bacterial infection, decreased susceptibility to parasitic infection, embryonic lethality prior to tooth bud stage, hemochromatosis, hydrometra, increased T-helper 1 cell number, increased gamma-delta T cell number, increased gamma-delta intraepithelial T cell number, increased interleukin-3 secretion, increased susceptibility to infection induced morbidity/mortality, increased tumor necrosis factor secretion, insulitis, small superior vagus ganglion [+]
View all ortholog results at Monarch