cd74 Phenotypes

Phenotypes

XB-GENEPAGE-922846

Gene Symbol: cd74 Gene Name: CD74 molecule

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: cd74 assayed (1 source)
Computed annotations: cd74 assayed (3 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (27 sources): abnormal T cell proliferation, abnormal T-helper 1 physiology, abnormal antigen presentation, abnormal antigen presentation via MHC class II, abnormal dendritic cell antigen presentation, abnormal level of surface class II molecules, abnormal lymph node cell ratio, abnormal positive T cell selection, abnormal professional antigen presenting cell physiology, arrested B cell differentiation, decreased B cell proliferation, decreased CD4-positive, alpha beta T cell number, decreased T cell proliferation, decreased body size, decreased cell proliferation, decreased interferon-gamma secretion, decreased interleukin-2 secretion, decreased susceptibility to experimental autoimmune encephalomyelitis, decreased susceptibility to type IV hypersensitivity reaction, defective assembly of class II molecules, hematopoietic system phenotype, immune system phenotype, increased CD8-positive, alpha-beta T cell number, increased T cell proliferation, increased immature B cell number, increased neutrophil cell number, increased susceptibility to experimental autoimmune encephalomyelitis [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (27 sources): abnormal T cell proliferation, abnormal T-helper 1 physiology, abnormal antigen presentation, abnormal antigen presentation via MHC class II, abnormal dendritic cell antigen presentation, abnormal level of surface class II molecules, abnormal lymph node cell ratio, abnormal positive T cell selection, abnormal professional antigen presenting cell physiology, arrested B cell differentiation, [+]