otx1 Phenotypes

Phenotypes

XB-GENEPAGE-939803

Gene Symbol: otx1 Gene Name: orthodenticle homeobox 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: otx1 manipulated (5 sources), otx1 assayed (9 sources)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xtr Wt + otx1 MO + vegetal yolk mass explant (4 sources), Xtr Wt + vegt MO + otx1 MO + vegetal yolk mass explant (4 sources), Xtr Wt + vegt + otx1 + animal cap explant (1 source), Xtr Wt + vegt + otx1 + animal cap explant (1 source), Xtr Wt + vegt + otx1 + animal cap explant (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (37 sources): abnormal cerebellar foliation, abnormal cerebral cortex morphology, abnormal cranium morphology, abnormal orbitosphenoid bone morphology, abnormal ovarian folliculogenesis, abnormal pituitary secretion, abnormal seminiferous tubule morphology, abnormal telencephalon development, abnormal third ventricle morphology, abnormal trigeminal V mesencephalic nucleus morphology, absent Harderian gland, absent ciliary process, absent lateral semicircular canal, arrest of spermatogenesis, behavior/neurological phenotype, circling, convulsive seizures, decreased brain size, decreased brain weight, decreased inferior colliculus size, decreased midbrain size, decreased superior colliculus size, delayed fertility, head shaking, hearing/vestibular/ear phenotype, increased cerebellar foliation, increased inferior colliculus size, increased superior colliculus size, meteorism, neonatal lethality, complete penetrance, nervous system phenotype, nonconvulsive seizures, postnatal lethality, incomplete penetrance, premature death, retina hyperplasia, small hippocampus, small ovary [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (37 sources): abnormal cerebellar foliation, abnormal cerebral cortex morphology, abnormal cranium morphology, abnormal orbitosphenoid bone morphology, abnormal ovarian folliculogenesis, abnormal pituitary secretion, abnormal seminiferous tubule morphology, abnormal telencephalon development, abnormal third ventricle morphology, abnormal trigeminal V mesencephalic nucleus morphology, [+]