Monarch Ortholog Phenotypes
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Mouse (36 sources):
abnormal bone marrow cell number,
abnormal circulating chemokine level,
abnormal common myeloid progenitor cell morphology,
abnormal embryonic erythropoiesis,
abnormal erythropoiesis,
abnormal megakaryocyte differentiation,
abnormal megakaryocyte morphology,
abnormal megakaryocyte progenitor cell morphology,
abnormal vitelline vasculature morphology,
atrioventricular septal defect,
cardiovascular system phenotype,
common atrioventricular valve,
decreased embryo size,
decreased platelet alpha-granule number,
decreased spleen white pulp amount,
embryonic lethality during organogenesis, complete penetrance,
embryonic lethality during organogenesis, incomplete penetrance,
hematopoietic system phenotype,
impaired hematopoiesis,
increased erythrocyte cell number,
increased granulocyte number,
increased heart weight,
increased hemoglobin concentration distribution width,
increased neutrophil cell number,
increased red blood cell distribution width,
increased spleen red pulp amount,
increased spleen weight,
lethality throughout fetal growth and development, complete penetrance,
lethality throughout fetal growth and development, incomplete penetrance,
no abnormal phenotype detected,
pale liver,
pale yolk sac,
pericardial edema,
perinatal lethality, incomplete penetrance,
small liver,
thin myocardium
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