prkra Phenotypes

Phenotypes

XB-GENEPAGE-940705

Gene Symbol: prkra Gene Name: protein activator of interferon induced protein kinase EIF2AK2

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (24 sources): Abnormal pyramidal sign, Bradykinesia, Cognitive impairment, Delayed speech and language development, Dysarthria, Dyskinesia, Dysphagia, Dysphonia, Gait disturbance, Hyperreflexia, Intellectual disability, Involuntary movements, Laryngeal dystonia, Limb dystonia, Limb pain, Lower limb pain, Morphological abnormality of the pyramidal tract, Motor delay, Orofacial dyskinesia, Parkinsonism, Postural tremor, Retrocollis, Torticollis, Unsteady gait [+]
Mouse (23 sources): abnormal blood urea nitrogen level, abnormal circulating alkaline phosphatase level, abnormal ear morphology, abnormal external auditory canal morphology, abnormal grip strength, abnormal middle ear ossicle morphology, abnormal neurocranium morphology, abnormal outer ear morphology, abnormal temporal bone zygomatic process morphology, decreased body size, decreased circulating alkaline phosphatase level, decreased startle reflex, embryonic lethality before implantation, complete penetrance, increased grip strength, increased or absent threshold for auditory brainstem response, prolonged RR interval, reduced fertility, round snout, small interparietal bone, small mandibular condyloid process, small mandibular coronoid process, turbinate hypoplasia, vision/eye phenotype [+]
View all ortholog results at Monarch