| Monarch Ortholog Phenotypes
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Human (32 sources):
Abnormal cerebellum morphology,
Abnormal pyramidal sign,
Abnormality of eye movement,
Action tremor,
Anxiety,
Ataxia,
Axial dystonia,
Behavioral abnormality,
Bradykinesia,
Cerebellar atrophy,
Cerebral atrophy,
Cerebral cortical atrophy,
Cognitive impairment,
Delusions,
Dementia,
Depression,
Dysarthria,
Dysdiadochokinesis,
Dysmetria,
Facial myokymia,
Gait disturbance,
Head tremor,
Hyperreflexia,
Intention tremor,
Limb dysmetria,
Parkinsonism,
Poor fine motor coordination,
Postural tremor,
Progressive cerebellar ataxia,
Sensorimotor neuropathy,
Tremor by anatomical site,
Unsteady gait
[+]
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Mouse (8 sources):
abnormal locomotor activation,
abnormal sinus arrhythmia,
cardiovascular system phenotype,
decreased circulating glucose level,
decreased heart rate variability,
decreased mean corpuscular hemoglobin,
decreased mean corpuscular volume,
shortened RR interval
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.