Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Phenotypes Gene Literature (14) GO Terms (8) Nucleotides (359) Proteins (27) Interactants (431) Wiki
XB-GENEPAGE-946621

hif1a     hypoxia inducible factor 1 subunit alpha

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormally decreased coiling of proximal tubule (1 source), abnormally simple of proximal tubule (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: hif1a assayed (1 source)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + hif1an MO (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (140 sources): abnormal T cell differentiation, abnormal angiogenesis, abnormal body temperature, abnormal brain vasculature morphology, abnormal cardiac muscle relaxation, abnormal cardiac outflow tract development, abnormal cartilage development, abnormal cerebral cortex morphology, abnormal cerebral hemisphere morphology, abnormal coronary vessel morphology, [+]