scarb2 Phenotypes

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Phenotypes

Gene Literature (1)

Nucleotides (97)

Interactants (193)

XB-GENEPAGE-948021

Gene Symbol: scarb2 Gene Name: scavenger receptor class B member 2

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: scarb2 assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (67 sources): Abdominal pain, Abnormal myocardium morphology, Abnormal pulmonary interstitial morphology, Abnormality of the orbital region, Action tremor, Anemia, Anorexia, Ascites, Ataxia, Avascular necrosis, Bilateral tonic-clonic seizure, Biliary tract obstruction, Bone pain, Bruising susceptibility, Cerebellar atrophy, Cirrhosis, Cutaneous photosensitivity, Delayed puberty, Delayed skeletal maturation, Dementia, Dysarthria, Dysphagia, Dyspnea, EEG with polyspike wave complexes, Epistaxis, Erlenmeyer flask deformity of the femurs, Focal segmental glomerulosclerosis, Gait ataxia, Generalized non-motor (absence) seizure, Generalized-onset seizure, Gingival bleeding, Glomerulopathy, Growth delay, Hematuria, Hepatomegaly, Hyperpigmentation of the skin, Hypersplenism, Hypertension, Increased bone mineral density, Increased circulating antibody level, Intellectual disability, Intention tremor, Kyphosis, Leukopenia, Limb ataxia, Macular atrophy, Mental deterioration, Morning myoclonic jerks, Multiple myeloma, Myoclonus, Nephropathy, Nephrotic syndrome, Osteoarthritis, Osteolysis, Osteopenia, Pancytopenia, Pathologic fracture, Pedal edema, Pericardial effusion, Postural tremor, Proteinuria, Pulmonary arterial hypertension, Pulmonary infiltrates, Renal insufficiency, Splenomegaly, Thrombocytopenia, Vertebral compression fracture [+]
Mouse (44 sources): abnormal Schwann cell morphology, abnormal adipose tissue amount, abnormal bone mineralization, abnormal circulating potassium level, abnormal distortion product otoacoustic emission, abnormal fasting circulating glucose level, abnormal grip strength, abnormal mean corpuscular hemoglobin, abnormal mean corpuscular volume, abnormal otolithic membrane morphology, abnormal phrenic nerve morphology, abnormal stria vascularis morphology, abnormal stria vascularis vasculature morphology, abnormal strial marginal cell morphology, abnormal ureter smooth muscle morphology, abnormal ureteropelvic junction morphology, abnormal urothelium morphology, abnormal vestibular hair cell physiology, absent endocochlear potential, absent otoliths, absent startle reflex, cochlear ganglion degeneration, cochlear inner hair cell degeneration, cochlear outer hair cell degeneration, deafness, decreased endocochlear potential, decreased exploration in new environment, decreased fasting circulating glucose level, decreased grip strength, decreased mean corpuscular hemoglobin, decreased mean corpuscular volume, decreased urine glucose level, decreased urine osmolality, dilated kidney calyx, enlarged lymph nodes, increased bone mineral content, increased erythrocyte cell number, increased lean body mass, leukocyturia, limb grasping, microgliosis, premature death, sensorineural hearing loss, stria vascularis degeneration [+]
View all ortholog results at Monarch