| Monarch Ortholog Phenotypes
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Human (18 sources):
Abdominal pain,
Abnormal nasolacrimal system morphology,
Abnormality of the thyroid gland,
Anemia,
B-cell lymphoma,
Constipation,
Fatigue,
Fever,
Gastric lymphoma,
Hyperhidrosis,
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Mouse (25 sources):
abnormal T cell activation,
abnormal T cell differentiation,
abnormal cytotoxic T cell physiology,
abnormal dendritic cell physiology,
abnormal humoral immune response,
abnormal immune cell physiology,
abnormal marginal zone B cell physiology,
abnormal neural fold elevation formation,
abnormal response to infection,
cellular phenotype,
decreased B cell proliferation,
decreased B-1 B cell number,
decreased T cell proliferation,
decreased activated T cell number,
decreased double-positive T cell number,
decreased follicular B cell number,
decreased marginal zone B cell number,
decreased mature B cell number,
decreased thymocyte number,
increased CD4-positive, alpha beta T cell number,
increased double-negative T cell number,
increased hindbrain apoptosis,
increased single-positive T cell number,
open neural tube,
perinatal lethality, incomplete penetrance
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.