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XB-GENEPAGE-953728
prdm12 PR domain containing 12
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| abnormal swimming behavior (2 sources), absent swimming behavior (2 sources) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Manual annotations: prdm12 manipulated (11 sources), prdm12 assayed (4 sources) |
| Computed annotations: prdm12 manipulated (3 sources), prdm12 assayed (19 sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + Flag-Mmu.prdm12 (5 sources), Xla Wt + prdm12 MO (4 sources), Xla Wt + Flag-Mmu.prdm12 (1 source), Xla Wt + prdm12 MO (1 source), Xla Wt + prdm12-EnR-Flag (1 source), Xla Wt + prdm12-EnR-Flag + animal cap explant (1 source), Xla Wt + prdm12-Flag - animal cap explant (1 source), Xla Wt + prdm12-VP16-Flag - animal cap explant (1 source), Xla Wt + VP16-Flag-prdm12 (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Human (4 sources): Corneal scarring, Corneal ulceration, Hypohidrosis, Recurrent infections |
| Mouse (12 sources): abnormal embryo size, abnormal neurite morphology, abnormal superior glossopharyngeal ganglion morphology, decreased neuron number, decreased sensory neuron number, hypoactivity, increased anxiety-related response, increased neuron apoptosis, neonatal lethality, complete penetrance, preweaning lethality, complete penetrance, [+] |
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View all ortholog results at Monarch |