| Monarch Ortholog Phenotypes
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Human (8 sources):
Abnormality of metabolism/homeostasis,
Hydronephrosis,
Hyperxanthinemia,
Myopathy,
Pyelonephritis,
Reduced xanthine dehydrogenase level,
Xanthine nephrolithiasis,
Xanthinuria
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Mouse (28 sources):
abnormal blood homeostasis,
abnormal involution of the mammary gland,
abnormal kidney development,
abnormal kidney morphology,
abnormal lactation,
abnormal lipid homeostasis,
abnormal mammary gland growth during lactation,
abnormal milk composition,
abnormal renal glomerulus morphology,
abnormal renal tubule epithelium morphology,
abnormal renal tubule morphology,
abnormal skeletal muscle morphology,
crystalluria,
decreased abdominal adipose tissue amount,
decreased body size,
dilated renal tubules,
homeostasis/metabolism phenotype,
hypoxia,
increased circulating alkaline phosphatase level,
increased circulating amylase level,
increased circulating creatinine level,
increased triglyceride level,
oxidative stress,
pale kidney,
postnatal lethality, complete penetrance,
premature death,
slow postnatal weight gain,
small kidney
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View all ortholog results at Monarch
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Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.