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Summary Expression Phenotypes Gene Literature (46) GO Terms (19) Nucleotides (85) Proteins (34) Interactants (214) Wiki
XB-GENEPAGE-957955

mre11     MRE11 homolog , double strand break repair nuclease

Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (47 sources): Abnormality of chromosome stability, Abnormality of ocular smooth pursuit, Absent Achilles reflex, Ataxia, Cerebellar atrophy, Cerebellar vermis hypoplasia, Chorea, Chromosomal breakage induced by ionizing radiation, Delayed speech and language development, Dilated fourth ventricle, [+]
Mouse (19 sources): abnormal cell cycle checkpoint function, abnormal class switch recombination, abnormal embryo development, abnormal heart development, cellular phenotype, chromosomal instability, decreased cell proliferation, decreased cellular sensitivity to ionizing radiation, embryonic growth arrest, embryonic lethality during organogenesis, complete penetrance, [+]

View all ortholog results at Monarch