abnormal dendritic spine morphology, abnormal embryo size, abnormal embryo turning, abnormal forebrain development, abnormal grip strength, abnormal hemoglobin content, abnormal hindbrain development, abnormal hypoglossal canal morphology, abnormal lean body mass, abnormal midbrain development, abnormal telencephalon morphology, abnormal total retina thickness, absent hypoglossal canal, absent hypoglossal nerve, decreased caudal vertebrae number, decreased circulating alanine transaminase level, decreased circulating alkaline phosphatase level, decreased circulating aspartate transaminase level, decreased circulating free fatty acids level, decreased circulating fructosamine level, decreased circulating glycerol level, decreased circulating iron level, decreased grip strength, decreased mean corpuscular volume, decreased startle reflex, decreased total retina thickness, dilated liver sinusoidal spaces, immune system phenotype, impaired cued conditioning behavior, impaired synaptic plasticity, improved glucose tolerance, increased CD8-positive, alpha-beta T cell number, increased bone mineral content, increased circulating alkaline phosphatase level, increased lean body mass, increased mean corpuscular hemoglobin, increased red blood cell distribution width, preweaning lethality, complete penetrance, preweaning lethality, incomplete penetrance, thin hypoglossal nerve