klf3 Phenotypes

Summary

Expression

Phenotypes

Gene Literature (3)

XB-GENEPAGE-961741

Gene Symbol: klf3 Gene Name: KLF transcription factor 3

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: klf3 assayed (4 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (40 sources): abnormal aortic valve morphology, abnormal blood flow velocity, abnormal blood pressure regulation, abnormal cell differentiation, abnormal epididymal fat pad morphology, abnormal gonadal fat pad morphology, abnormal retroperitoneal fat pad morphology, abnormal ventricle myocardium morphology, cardiac hypertrophy, cardiovascular system phenotype, decreased abdominal fat pad weight, decreased erythrocyte cell number, decreased hemoglobin content, decreased mean systemic arterial blood pressure, decreased percent body fat/body weight, decreased survivor rate, decreased systemic arterial blood pressure, hematoma, hematopoietic system phenotype, increased atrioventricular cushion size, increased brain weight, increased cardiac muscle contractility, increased cardiac output, increased heart right ventricle size, increased heart weight, increased kidney weight, increased liver weight, increased lung weight, increased oxygen consumption, increased red blood cell distribution width, increased spleen weight, lethality throughout fetal growth and development, complete penetrance, lethality throughout fetal growth and development, incomplete penetrance, neonatal lethality, incomplete penetrance, no abnormal phenotype detected, postnatal lethality, incomplete penetrance, premature death, preweaning lethality, incomplete penetrance, slow postnatal weight gain, thick aortic valve cusps [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (40 sources): abnormal aortic valve morphology, abnormal blood flow velocity, abnormal blood pressure regulation, abnormal cell differentiation, abnormal epididymal fat pad morphology, abnormal gonadal fat pad morphology, abnormal retroperitoneal fat pad morphology, abnormal ventricle myocardium morphology, cardiac hypertrophy, cardiovascular system phenotype, [+]