Corneal arcus, Coronary artery aneurysm, Coronary artery atherosclerosis, Dyspnea, Heart murmur, Hepatic steatosis, Hypercholesterolemia, Hyperlipidemia, Hypertension, Increased LDL cholesterol concentration, Mitral regurgitation, Myocardial infarction, Myocardial steatosis, Optic neuropathy, Peripheral arterial stenosis, Precocious atherosclerosis, Premature arteriosclerosis, Premature coronary artery atherosclerosis, Renal artery stenosis, Renal steatosis, Sudden cardiac death, Supravalvular aortic stenosis, Tendon xanthomatosis, Xanthelasma, Xanthomatosis

abnormal fat pad morphology, abnormal lipid homeostasis, abnormal microglial cell morphology, abnormal retina pigment epithelium morphology, abnormal short term spatial reference memory, abnormal spatial learning, abnormal spatial working memory, abnormal synapse morphology, abnormal synaptic bouton morphology, abnormal triglyceride level, amyloid beta deposits, decreased circulating interleukin-10 level, decreased circulating unsaturated transferrin level, decreased lean body mass, decreased susceptibility to weight gain, homeostasis/metabolism phenotype, increased cholesterol level, increased circulating VLDL triglyceride level, increased circulating alanine transaminase level, increased circulating glucose level, increased circulating interleukin-1 beta level, increased circulating interleukin-6 level, increased circulating iron level, increased circulating tumor necrosis factor level, increased grip strength, increased hepatocyte apoptosis, increased liver cholesterol level, increased liver triglyceride level, increased liver weight, increased macrophage derived foam cell number, increased percent body fat/body weight, increased susceptibility to atherosclerosis, increased susceptibility to weight gain, macrovesicular hepatic steatosis, maternal effect, microvesicular hepatic steatosis, no abnormal phenotype detected, oxidative stress, photoreceptor outer segment degeneration, thick skin