Gait disturbance, Generalized amyotrophy, Global developmental delay, Hypertrophic cardiomyopathy, Intellectual disability, Muscle flaccidity, Myocardial fibrosis, Myocardial necrosis, Pes cavus, Proximal muscle weakness, Visual impairment, Wolff-Parkinson-White syndrome

decreased gonadal fat pad weight, decreased hepatic glucose production, decreased litter size, decreased liver glycogen level, decreased locomotor activity, decreased percent body fat/body weight, decreased white fat cell lipid droplet size, enhanced behavioral response to xenobiotic, enlarged myocardial fiber, improved glucose tolerance, increased carbon dioxide production, increased cellular glucose import, increased circulating alanine transaminase level, increased energy expenditure, increased heart weight, increased hepatocyte apoptosis, increased liver triglyceride level, increased liver weight, increased oxygen consumption, increased respiratory quotient, increased susceptibility to weight gain, intermingled spleen red and white pulp, pale liver, premature death, thick ventricular wall