| Monarch Ortholog Phenotypes
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Human (29 sources):
Abnormality of the liver,
Anemia,
Blurred vision,
Cholestasis,
Congestive heart failure,
Corneal opacity,
Coronary artery atherosclerosis,
Decreased HDL cholesterol concentration,
EMG abnormality,
Edema,
Generalized amyloid deposition,
Hematuria,
Hemiplegia/hemiparesis,
Hepatic amyloidosis,
Hepatomegaly,
Hypertension,
Lymphadenopathy,
Myocardial infarction,
Nephropathy,
Nephrotic syndrome,
Peptic ulcer,
Polyneuropathy,
Premature coronary artery atherosclerosis,
Proteinuria,
Renal amyloidosis,
Renal insufficiency,
Skin rash,
Splenomegaly,
Xanthomatosis
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Mouse (4 sources):
abnormal vascular wound healing,
decreased cholesterol efflux,
decreased circulating phospholipid level,
homeostasis/metabolism phenotype
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.