cul4b Phenotypes

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Phenotypes

Gene Literature (1)

Nucleotides (304)

Interactants (290)

XB-GENEPAGE-963627

Gene Symbol: cul4b Gene Name: cullin 4B

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (82 sources): Abdominal obesity, Abnormal cerebral white matter morphology, Abnormal earlobe morphology, Abnormal hair pattern, Abnormal pinna morphology, Abnormality of the musculature, Absent speech, Acanthosis nigricans, Aggressive behavior, Biparietal narrowing, Blepharophimosis, Brachydactyly, Broad-based gait, Bulbous nose, Cachexia, Camptodactyly of finger, Cerebellar vermis atrophy, Clinodactyly of the 5th finger, Coarse facial features, Cortical dysplasia, Cryptorchidism, Cubitus valgus, Decreased testicular size, Delayed puberty, Delayed speech and language development, Depressed nasal bridge, Distal lower limb amyotrophy, Down-sloping shoulders, Downslanted palpebral fissures, EEG abnormality, Epicanthus, Gait ataxia, Generalized hypotonia, Gynecomastia, High forehead, High palate, Hyperactivity, Hyperhidrosis, Hypogonadism, Hypoplasia of penis, Hypoplasia of the corpus callosum, Hypospadias, Hypotonia, Immunodeficiency, Intellectual disability, Intellectual disability, moderate, Intellectual disability, severe, Kyphosis, Macrocephaly, Macroglossia, Mandibular prognathia, Microcephaly, Micropenis, Mood swings, Motor delay, Neurological speech impairment, Obesity, Open bite, Pes cavus, Pes planus, Polymicrogyria, Prominent nose, Relative macrocephaly, Sandal gap, Scoliosis, Seizure, Short foot, Short neck, Short palm, Short philtrum, Short stature, Simplified gyral pattern, Small hand, Striae distensae, Synophrys, Thick lower lip vermilion, Toe syndactyly, Tremor, Ventriculomegaly, Wide mouth, obsolete Joint hyperflexibility, obsolete Joint laxity [+]
Mouse (33 sources): abnormal dendrite morphology, abnormal dendritic spine morphology, abnormal developmental patterning, abnormal dosage compensation, by inactivation of X chromosome, abnormal ectoderm development, abnormal embryo development, abnormal embryonic tissue morphology, abnormal extraembryonic tissue morphology, abnormal placenta labyrinth morphology, abnormal spatial learning, abnormal spatial working memory, abnormal visceral yolk sac morphology, abnormal vitelline vasculature morphology, absent ectoplacental cone, decreased body size, decreased cell proliferation, decreased embryo size, decreased fetal size, decreased neuron number, disorganized extraembryonic tissue, disorganized placental labyrinth, embryonic growth arrest, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, failure of primitive streak formation, fetal growth retardation, increased embryonic tissue cell apoptosis, increased susceptibility to pharmacologically induced seizures, lethality during fetal growth through weaning, incomplete penetrance, lethality throughout fetal growth and development, complete penetrance, lethality throughout fetal growth and development, incomplete penetrance, no abnormal phenotype detected, pale placenta [+]
View all ortholog results at Monarch