pip4k2c Phenotypes

Phenotypes

XB-GENEPAGE-964848

Gene Symbol: pip4k2c Gene Name: phosphatidylinositol-5-phosphate 4-kinase, type II, gamma

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: pip4k2c assayed (10 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (25 sources): abnormal T cell activation, abnormal circulating chemokine level, chronic inflammation, decreased blood urea nitrogen level, decreased regulatory T cell number, growth/size/body region phenotype, homeostasis/metabolism phenotype, increased CD4-positive, alpha beta T cell number, increased CD8-positive, alpha-beta T cell number, increased IgG3 level, increased T cell proliferation, increased T-helper cell number, increased circulating aspartate transaminase level, increased circulating interferon-gamma level, increased circulating interleukin-10 level, increased circulating interleukin-12 level, increased circulating interleukin-12b level, increased circulating interleukin-2 level, increased circulating interleukin-4 level, increased fasting circulating glucose level, increased interferon-gamma secretion, increased interleukin-17 secretion, increased startle reflex, pale liver, salivary gland inflammation [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (25 sources): abnormal T cell activation, abnormal circulating chemokine level, chronic inflammation, decreased blood urea nitrogen level, decreased regulatory T cell number, growth/size/body region phenotype, homeostasis/metabolism phenotype, increased CD4-positive, alpha beta T cell number, increased CD8-positive, alpha-beta T cell number, increased IgG3 level, [+]