dnmt1 Phenotypes

Phenotypes

XB-GENEPAGE-965561

Gene Symbol: dnmt1 Gene Name: DNA methyltransferase 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: dnmt1 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (41 sources): Abnormal cerebral white matter morphology, Abnormal cerebrospinal fluid morphology, Abnormality of mitochondrial metabolism, Apathy, Ataxia, Atrophy/Degeneration affecting the brainstem, Babinski sign, Cataplexy, Cataract, Cerebellar atrophy, Cerebral atrophy, Decreased number of peripheral myelinated nerve fibers, Delirium, Dementia, Depression, Dilated third ventricle, Excessive daytime somnolence, Head tremor, Hearing impairment, Hyperreflexia, Hyporeflexia, Impulsivity, Irritability, Memory impairment, Mental deterioration, Narcolepsy, Neuronal loss in central nervous system, Nystagmus, obsolete Excessive daytime sleepiness, Optic atrophy, Osteomyelitis, Peripheral neuropathy, Predominantly lower limb lymphedema, Primitive reflex, Pseudobulbar signs, Psychosis, Resting tremor, Sensorineural hearing impairment, Sensory neuropathy, Spasticity, Urinary incontinence [+]
View all ortholog results at Monarch

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Human (41 sources): Abnormal cerebral white matter morphology, Abnormal cerebrospinal fluid morphology, Abnormality of mitochondrial metabolism, Apathy, Ataxia, Atrophy/Degeneration affecting the brainstem, Babinski sign, Cataplexy, Cataract, Cerebellar atrophy, [+]