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Summary Expression Phenotypes Gene Literature (529) GO Terms (11) Nucleotides (1117) Proteins (42) Interactants (998) Wiki
XB-GENEPAGE-966886

rho     rhodopsin

Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormal photoreceptor layer morphology (3 sources), abnormal retinal rod cell morphology (3 sources), absent retinal rod cell (3 sources), increased thickness of the blastocoel roof (2 sources), abnormal animal cap morphology (1 source), abnormal blastocoel roof morphology (1 source), abnormal cell division (1 source), abnormal cell morphology (1 source), abnormal epithelial cell (1 source), abnormally anterioralized embryo (1 source), abnormally decreased number of filamentous actin in the blastocoel roof (1 source), abnormally delayed closure of blastopore (1 source), abnormally increased number of filamentous actin in the blastocoel roof (1 source), abnormally localised head (1 source), absent upper blastopore lip (1 source), duplicated anterior-posterior axis (1 source), duplicated head (1 source), increased cell population proliferation in epithelium (1 source), increased pigmentation in the animal hemisphere (1 source)
Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: rho manipulated (6 sources), rho assayed (23 sources)
Computed annotations: rho assayed (3 sources)
Diseases
Diseases from the human disease ontology (DO) manually associated with phenotypes from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
retinitis pigmentosa (3AP sources, 5 EP sources)
Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + rho CRISPR (4 sources), Xla Wt + Tg(Hsa.rhoaQ63L:GFP (4 sources), Xla Wt + rhoa (3 sources), Xla Wt + rhoa (3 sources), Xla Wt + rho CRISPR (2 sources), Xla Wt + dnHsa.rhoa (2 sources), Xla Wt + rhoa + dnbmpr1a (1 source), Xla Wt + dnrhoa (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (47 sources): Abnormal electroretinogram, Abnormal fundus morphology, Abnormal retinal morphology, Abnormal retinal vascular morphology, Abnormal testis morphology, Abnormality of fundus pigmentation, Abnormality of macular pigmentation, Abnormality of retinal pigmentation, Anteverted nares, Atypical scarring of skin, [+]
Mouse (40 sources): abnormal a-wave shape, abnormal cone electrophysiology, abnormal eye development, abnormal eye electrophysiology, abnormal photoreceptor outer segment morphology, abnormal retina cone cell morphology, abnormal retina inner nuclear layer morphology, abnormal retina layer morphology, abnormal retina outer nuclear layer morphology, abnormal retina photoreceptor layer morphology, [+]

View all ortholog results at Monarch