xrcc6 Phenotypes

Phenotypes

XB-GENEPAGE-970898

Gene Symbol: xrcc6 Gene Name: X-ray repair complementing defective repair in Chinese hamster cells 6

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: xrcc6 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (27 sources): abnormal T cell differentiation, abnormal bone marrow cell morphology/development, abnormal diencephalon morphology, abnormal immune system organ morphology, abnormal nursing, absent immature B cells, absent mature B cells, absent pre-B cells, arrested B cell differentiation, decreased body size, decreased cell proliferation, decreased litter size, decreased single-positive T cell number, decreased spleen white pulp amount, decreased thymocyte number, early cellular replicative senescence, increased T cell derived lymphoma incidence, increased cellular sensitivity to gamma-irradiation, increased cellular sensitivity to ionizing radiation, increased double-positive T cell number, increased neuron apoptosis, nervous system phenotype, proportional dwarf, slow postnatal weight gain, small lymph nodes, small spleen, small thymus [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (27 sources): abnormal T cell differentiation, abnormal bone marrow cell morphology/development, abnormal diencephalon morphology, abnormal immune system organ morphology, abnormal nursing, absent immature B cells, absent mature B cells, absent pre-B cells, arrested B cell differentiation, decreased body size, [+]