cryab Phenotypes

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Phenotypes

Gene Literature (0)

Nucleotides (84)

Interactants (42)

XB-GENEPAGE-971378

Gene Symbol: cryab Gene Name: crystallin alpha B

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: cryab assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (45 sources): Abnormal circulating creatine kinase concentration, Abnormality of neutrophils, Accumulation of muscle fiber desmin, Apnea, Autophagic vacuoles, Axial muscle weakness, Cardiomyopathy, Cataract, Decreased Achilles reflex, Developmental cataract, Difficulty walking, Dilated cardiomyopathy, Distal muscle weakness, Dysphagia, Dysphonia, EMG abnormality, EMG: myopathic abnormalities, Elevated circulating creatine kinase concentration, Facial diplegia, Flexion contracture, Foot dorsiflexor weakness, Hypertrophic cardiomyopathy, Hyporeflexia, Increased variability in muscle fiber diameter, Late-onset proximal muscle weakness, Limb-girdle muscle weakness, Lipoatrophy, Mitral regurgitation, Muscle fiber inclusion bodies, Muscle fiber splitting, Muscle stiffness, Muscular dystrophy, Myopathy, Neck muscle weakness, Palmoplantar keratoderma, Posterior capsular cataract, Posterior polar cataract, Progressive distal muscle weakness, Progressive proximal muscle weakness, Respiratory insufficiency, Respiratory insufficiency due to muscle weakness, Retinal dystrophy, Rigidity, Sensorineural hearing impairment, Weak cry [+]
Mouse (20 sources): abnormal Z line morphology, abnormal atrial thrombosis, abnormal lens epithelium morphology, abnormal lens fiber morphology, abnormal myocardial fiber morphology, abnormal reticulophagy, cardiac hypertrophy, decreased cardiac muscle contractility, decreased cardiac muscle relaxation, decreased grip strength, dilated heart, disorganized secondary lens fibers, dystrophic cardiac calcinosis, enlarged myocardial fiber, liver vascular congestion, premature death, pulmonary vascular congestion, skeletal muscle fiber necrosis, skeletal muscle fibrosis, subcutaneous edema [+]
View all ortholog results at Monarch