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XB-GENEPAGE-972342
fbxo45 F-box protein 45
Anatomical Phenotypes
Phenotypes manually curated with terms from the Xenopus phenotype ontology
covering anatomical, gene ontology, and neurobehavioral phenotypes.
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| decreased size of the forebrain (2 sources), decreased size of the eye (1 source), decreased size of the midbrain (1 source), increased apoptosis in embryo (1 source) |
| Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.
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| Computed annotations: fbxo45 assayed (2 sources) |
| Diseases
Diseases from the human disease ontology (DO) manually associated with phenotypes
from disease models. Sources are grouped by anatomical (AP) and expression (EP) phenotypes.
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| disease of mental health (4AP sources) |
| Experiments (Reagents)
These are short form descriptions of experiments using reagents targeting
the gene of interest.
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| Xla Wt + fbxo45 MO (3 sources), Xla Wt + fbxo45 MO + ncbp2 MO (1 source) |
| Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
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| Mouse (15 sources): abnormal axon fasciculation, abnormal cortical plate morphology, abnormal motor neuron innervation pattern, abnormal nervous system tract morphology, abnormal neuromuscular synapse morphology, abnormal sensory neuron innervation pattern, abnormal spinal cord grey matter morphology, abnormal telencephalon development, absent anterior commissure, absent brain internal capsule, [+] |