lars1 leucyl-tRNA synthetase 1
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
|Computed annotations: lars1 assayed (1 source)|
|Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (20 sources):
Abnormality of the coagulation cascade,
Acute hepatic failure,
Delayed gross motor development,
Elevated hepatic transaminase,
Failure to thrive,
Global developmental delay, Hepatic steatosis, Hepatomegaly, Lactic acidosis, Long toe, Macrocytic anemia, Microcephaly, Muscular hypotonia, Seizure, Sensorineural hearing impairment[+]
|Mouse (2 sources): decreased circulating glucose level, preweaning lethality, complete penetrance|
View all ortholog results at Monarch