| Monarch Ortholog Phenotypes
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Human (22 sources):
4-Hydroxyphenylpyruvic aciduria,
Abnormality of amino acid metabolism,
Abnormality of the nail,
Abnormality of the skin,
Ataxia,
Behavioral abnormality,
Corneal opacity,
Growth delay,
Herpetiform corneal ulceration,
Hyperhidrosis,
Hyperkeratosis,
Hypertyrosinemia,
Intellectual disability,
Malar flattening,
Microcephaly,
Neurological speech impairment,
Nystagmus,
Palmoplantar keratoderma,
Photophobia,
Seizure,
Tremor,
Visual loss
[+]
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Mouse (5 sources):
abnormal locomotor activation,
increased grip strength,
persistence of hyaloid vascular system,
preweaning lethality, incomplete penetrance,
prolonged RR interval
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.