gatm Phenotypes

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Phenotypes

Gene Literature (4)

Nucleotides (1013)

Interactants (320)

XB-GENEPAGE-974513

Gene Symbol: gatm Gene Name: glycine amidinotransferase (L-arginine:glycine amidinotransferase)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: gatm assayed (14 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (8 sources): Autism, Delayed speech and language development, Failure to thrive, Global developmental delay, Gowers sign, Intellectual disability, Organic aciduria, Reduced brain creatine level by MRS
Mouse (41 sources): abnormal circulating alkaline phosphatase level, abnormal circulating potassium level, abnormal duodenum crypts of Lieberkuhn morphology, abnormal enterocyte proliferation, abnormal gluconeogenesis, abnormal grip strength, abnormal locomotor activation, abnormal prepulse inhibition, abnormal red blood cell distribution width, abnormal urine amino acid level, decreased body length, decreased body mass index, decreased circulating alkaline phosphatase level, decreased circulating glucose level, decreased circulating unsaturated transferrin level, decreased colon length, decreased creatine level, decreased grip strength, decreased liver triglyceride level, decreased locomotor activity, decreased red blood cell distribution width, decreased startle reflex, decreased susceptibility to diet-induced obesity, decreased susceptibility to hepatic steatosis, decreased urine creatine level, decreased urine creatinine level, decreased white adipose tissue amount, growth/size/body region phenotype, homeostasis/metabolism phenotype, immune system phenotype, improved glucose tolerance, increased adipocyte glucose uptake, increased anxiety-related response, increased enterocyte apoptosis, increased muscle cell glucose uptake, increased physiological sensitivity to xenobiotic, increased pulmonary respiratory rate, increased sensitivity to xenobiotic induced morbidity/mortality, increased susceptibility to induced colitis, increased susceptibility to weight loss, increased thigmotaxis [+]
View all ortholog results at Monarch