dusp1 Phenotypes

Summary

Expression

Phenotypes

Gene Literature (5)

XB-GENEPAGE-975055

Gene Symbol: dusp1 Gene Name: dual specificity phosphatase 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: dusp1 assayed (8 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (50 sources): abnormal cellular respiration, abnormal chemokine level, abnormal circulating alanine transaminase level, abnormal dendrite morphology, abnormal depression-related behavior, abnormal innate immunity, abnormal interleukin level, abnormal locomotor activation, abnormal muscle development, abnormal muscle regeneration, abnormal myoblast differentiation, abnormal nitric oxide homeostasis, abnormal superior cervical ganglion morphology, decreased abdominal fat pad weight, decreased anxiety-related response, decreased circulating alanine transaminase level, decreased circulating free fatty acids level, decreased epididymal fat pad weight, decreased fat cell size, decreased liver weight, decreased myoblast proliferation, decreased skeletal muscle fiber diameter, decreased skeletal muscle fiber size, decreased susceptibility to age related obesity, decreased susceptibility to diet-induced obesity, decreased susceptibility to hepatic steatosis, decreased systemic arterial systolic blood pressure, homeostasis/metabolism phenotype, immune system phenotype, increased circulating interferon-gamma level, increased circulating interleukin-10 level, increased circulating interleukin-6 level, increased circulating tumor necrosis factor level, increased energy expenditure, increased granulocyte number, increased hepatic glucose production, increased interleukin-1 beta secretion, increased interleukin-6 secretion, increased mast cell degranulation, increased neuron apoptosis, increased prostaglandin level, increased respiratory quotient, increased sensitivity to induced morbidity/mortality, increased sensitivity to xenobiotic induced morbidity/mortality, increased susceptibility to endotoxin shock, increased susceptibility to induced arthritis, increased susceptibility to type I hypersensitivity reaction, increased tumor necrosis factor secretion, small liver, thick pulmonary interalveolar septum [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (50 sources): abnormal cellular respiration, abnormal chemokine level, abnormal circulating alanine transaminase level, abnormal dendrite morphology, abnormal depression-related behavior, abnormal innate immunity, abnormal interleukin level, abnormal locomotor activation, abnormal muscle development, abnormal muscle regeneration, [+]