dlg3 Phenotypes

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Phenotypes

Gene Literature (0)

Nucleotides (257)

Interactants (43)

XB-GENEPAGE-977251

Gene Symbol: dlg3 Gene Name: discs, large homolog 3

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (46 sources): 2-3 toe syndactyly, Attention deficit hyperactivity disorder, Autistic behavior, Babinski sign, Behavioral abnormality, Bilateral tonic-clonic seizure, Broad nasal tip, Clinodactyly of the 2nd toe, Delayed eruption of teeth, Delayed speech and language development, Depressed nasal bridge, Downslanted palpebral fissures, Drooling, Enuresis, Facial palsy, Generalized hypotonia, Generalized non-motor (absence) seizure, Global developmental delay, High palate, Hypotonia, Intellectual disability, Intellectual disability, moderate, Intellectual disability, profound, Intellectual disability, severe, Long palpebral fissure, Long philtrum, Macrocephaly, Meckel diverticulum, Midface retrusion, Mild neurosensory hearing impairment, Moderate sensorineural hearing impairment, Narrow chest, Obesity, Periorbital fullness, Pes planus, Poor speech, Pyloric stenosis, Seizure, Shortening of all distal phalanges of the fingers, Small for gestational age, Strabismus, Thick lower lip vermilion, Thin upper lip vermilion, Upslanted palpebral fissure, Urinary incontinence, Widened subarachnoid space [+]
Mouse (15 sources): abnormal axon morphology, abnormal barrel cortex morphology, abnormal forebrain development, abnormal innervation, abnormal locomotor activation, abnormal long term potentiation, abnormal neocortex size, abnormal somatosensory cortex morphology, abnormal spatial learning, abnormal synapse morphology, caudal body truncation, decreased excitatory postsynaptic current amplitude, failure of initiation of embryo turning, increased lean body mass, prolonged excitatory postsynaptic current decay time [+]
View all ortholog results at Monarch