| Monarch Ortholog Phenotypes
|
Human (52 sources):
Abnormal isoelectric focusing of serum transferrin,
Abnormal rib cage morphology,
Abnormality of the dentition,
Aggressive behavior,
Brachycephaly,
Coxa valga,
Diastema,
Downslanted palpebral fissures,
Everted lower lip vermilion,
Failure to thrive,
Generalized hypotonia,
Gingival overgrowth,
Hirsutism,
Intellectual disability, progressive,
Intellectual disability, severe,
Long eyelashes,
Low hanging columella,
Macrocephaly,
Macrodontia,
Macrotia,
Microcephaly,
Midfrontal capillary hemangioma,
Motor stereotypy,
Open mouth,
Osteopenia,
Pectus excavatum,
Pes planus,
Posteriorly rotated ears,
Prominent nasal bridge,
Protruding tongue,
Proximal placement of thumb,
Reduced antithrombin III activity,
Reduced factor IX activity,
Reduced factor XI activity,
Reduced factor XII activity,
Retrognathia,
Seizure,
Self-mutilation,
Sensorineural hearing impairment,
Short neck,
Short stature,
Slender long bone,
Sparse hair,
Spasticity,
Tall stature,
Thick eyebrow,
Thin vermilion border,
Thoracolumbar kyphoscoliosis,
Type II transferrin isoform profile,
Unsteady gait,
Ventricular septal defect,
Wide mouth
[+]
|
Mouse (17 sources):
abnormal digestion,
abnormal locomotor behavior,
abnormal maternal nurturing,
abnormal muscle development,
arrest of male meiosis,
decreased body size,
decreased fetal size,
decreased grip strength,
delayed bone ossification,
enlarged lymph nodes,
increased partial thromboplastin time,
lethality throughout fetal growth and development, incomplete penetrance,
nervous system phenotype,
postnatal lethality, complete penetrance,
postnatal lethality, incomplete penetrance,
prenatal lethality, incomplete penetrance,
reduced female fertility
[+]
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View all ortholog results at Monarch
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These phenotypes are associated with this gene with a has phenotype relation via Monarch.