gadd45b Phenotypes

XB-GENEPAGE-979558

Gene Symbol: gadd45b Gene Name: growth arrest and DNA damage inducible beta

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: gadd45b assayed (11 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (16 sources): abnormal CD4-positive, alpha-beta T cell physiology, abnormal T-helper 1 cell differentiation, abnormal T-helper 1 physiology, abnormal T-helper 2 physiology, abnormal bone marrow cell morphology/development, abnormal dendritic cell physiology, decreased interferon-gamma secretion, decreased interleukin-12 secretion, decreased interleukin-2 secretion, decreased interleukin-4 secretion, decreased interleukin-6 secretion, increased T cell proliferation, increased interferon-gamma secretion, increased susceptibility to experimental autoimmune encephalomyelitis, renal glomerular immunoglobulin deposits, spleen hyperplasia [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (16 sources): abnormal CD4-positive, alpha-beta T cell physiology, abnormal T-helper 1 cell differentiation, abnormal T-helper 1 physiology, abnormal T-helper 2 physiology, abnormal bone marrow cell morphology/development, abnormal dendritic cell physiology, decreased interferon-gamma secretion, decreased interleukin-12 secretion, decreased interleukin-2 secretion, decreased interleukin-4 secretion, [+]