Adenoma sebaceum, Angiofibromas, Aplasia/Hypoplasia of the corpus callosum, Arrhythmia, Ascites, Astrocytoma, Atelectasis, Attention deficit hyperactivity disorder, Atypical behavior, Autism, Cafe-au-lait spot, Cardiac rhabdomyoma, Cerebral calcification, Chest pain, Chordoma, Chylopericardium, Chylothorax, Cognitive impairment, Confetti-like hypopigmented macules, Congestive heart failure, Cortical dysplasia, Cortical tubers, Cough, Dental enamel pits, Dyspnea, EEG abnormality, Emphysema, Ependymoma, Epileptic spasm, Fatigue, Fever, Gastrointestinal hemorrhage, Gingival fibromatosis, Gingivitis, Global developmental delay, Hematuria, Hemimegalencephaly, Hemoptysis, Hydrocephalus, Hypopigmented skin patches, Hypothyroidism, Increased intracranial pressure, Infantile spasms, Intellectual disability, Iris coloboma, Lymphadenopathy, Lymphedema, Macrodactyly, Macule, Multiple cafe-au-lait spots, Multiple renal cysts, Neoplasm of the pancreas, Nevus flammeus, Optic atrophy, Optic nerve glioma, Papule, Pneumothorax, Precocious puberty, Prominent occiput, Pulmonary infiltrates, Pulmonary lymphangiomyomatosis, Recurrent respiratory infections, Renal angiomyolipoma, Renal cell carcinoma, Renal cyst, Renal insufficiency, Renal neoplasm, Respiratory insufficiency, Restrictive ventilatory defect, Retinal hamartoma, Seizure, Shagreen patch, Skin tags, Specific learning disability, Subcutaneous nodule, Subependymal giant-cell astrocytoma, Subependymal nodules, Subungual fibromas, Ungual fibroma, Vascular dilatation, Wolff-Parkinson-White syndrome

abnormal pancreatic islet morphology, abnormal Purkinje cell morphology, abnormal response to novel object, abnormal response to social novelty, abnormal seminiferous tubule epithelium morphology, abnormal seminiferous tubule morphology, abnormal Sertoli cell morphology, abnormal social investigation, abnormal spatial learning, abnormal vascular development, behavior/neurological phenotype, decreased coping response, decreased embryo size, decreased male germ cell number, decreased myocardial infarct size, decreased testis weight, dilated vasculature, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, embryonic lethality during organogenesis, incomplete penetrance, enhanced long term potentiation, environmentally induced seizures, heart hyperplasia, improved glucose tolerance, incomplete rostral neuropore closure, increased adenoma incidence, increased apoptosis, increased brain size, increased brain weight, increased circulating glucose level, increased endometrial gland number, increased extremity angiosarcoma incidence, increased hamartoma incidence, increased hepatic hemangioma incidence, increased insulin sensitivity, increased kidney tumor incidence, increased lung adenoma incidence, increased lung tumor incidence, increased metastatic potential, increased myocardial infarct size, increased pancreatic beta cell mass, increased renal carcinoma incidence, increased renal cystadenoma incidence, increased skin hamartoma incidence, increased tumor incidence, increased uterus leiomyoma incidence, increased uterus weight, increased vertical activity, lethality throughout fetal growth and development, complete penetrance, lethality throughout fetal growth and development, incomplete penetrance, liver hypoplasia, nervous system phenotype, no abnormal phenotype detected, open neural tube, pancreatic islet hyperplasia, postnatal lethality, complete penetrance, postnatal lethality, incomplete penetrance, premature death, prenatal lethality, complete penetrance, preweaning lethality, complete penetrance, Purkinje cell degeneration, reduced long term depression, slow postnatal weight gain, thick myocardium