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Summary Expression Phenotypes Gene Literature (64) GO Terms (5) Nucleotides (76) Proteins (37) Interactants (69) Wiki
XB-GENEPAGE-981915

wnk4     WNK lysine deficient protein kinase 4

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: wnk4 assayed (2 sources)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (5 sources): Hyperchloremia, Hyperchloremic metabolic acidosis, Hyperkalemia, Hypertension, Pseudohypoaldosteronism
Mouse (14 sources): abnormal blood homeostasis, abnormal carbon dioxide level, abnormal distal convoluted tubule morphology, alkalemia, cardiovascular system phenotype, decreased circulating bicarbonate level, decreased physiological sensitivity to xenobiotic, decreased systemic arterial diastolic blood pressure, decreased systemic arterial systolic blood pressure, homeostasis/metabolism phenotype, [+]

View all ortholog results at Monarch