| Monarch Ortholog Phenotypes
|
Human (54 sources):
Abnormal diaphysis morphology,
Abnormal fingernail morphology,
Abnormal toenail morphology,
Abnormality of dental enamel,
Abnormality of the dentition,
Abnormality of the metaphysis,
Anteverted nares,
Brachydactyly,
Carious teeth,
Clinodactyly of the 5th finger,
Cone-shaped epiphyses of the phalanges of the hand,
Craniosynostosis,
Depressed nasal bridge,
Disproportionate short-limb short stature,
Dolichocephaly,
Epicanthus,
Everted lower lip vermilion,
Finger syndactyly,
Flat acetabular roof,
Frontal bossing,
Full cheeks,
High forehead,
High hypermetropia,
Hypermetropia,
Hypodontia,
Hypoplasia of the corpus callosum,
Hypotelorism,
Joint hyperflexibility,
Low-set ears,
Microdontia,
Midface retrusion,
Motor delay,
Myopia,
Narrow chest,
Nystagmus,
Osteoporosis,
Pectus excavatum,
Postaxial polydactyly,
Prominent occiput,
Protuberant abdomen,
Respiratory distress,
Rhizomelia,
Sandal gap,
Short distal phalanx of finger,
Short metacarpal,
Short metatarsal,
Short phalanx of finger,
Short stature,
Short thorax,
Sparse hair,
Taurodontia,
Telecanthus,
Wide nasal bridge,
Widely spaced teeth
[+]
|
|
Mouse (9 sources):
abnormal embryo size,
abnormal embryo turning,
abnormal forebrain development,
abnormal heart looping,
abnormal midbrain development,
abnormal visceral yolk sac morphology,
embryonic lethality during organogenesis, complete penetrance,
increased exploration in new environment,
preweaning lethality, complete penetrance
|
View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.