plcg1 Phenotypes

XB-GENEPAGE-982495

Gene Symbol: plcg1 Gene Name: phospholipase C gamma 1

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: plcg1 assayed (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (17 sources): abnormal T cell activation, abnormal embryonic hematopoiesis, abnormal proerythroblast morphology, abnormal vascular endothelial cell development, abnormal vasculogenesis, absent visceral yolk sac blood islands, decreased body size, decreased regulatory T cell number, dermatitis, ear inflammation, embryonic growth arrest, embryonic growth retardation, embryonic lethality during organogenesis, complete penetrance, embryonic lethality, complete penetrance, increased CD4-positive, alpha beta T cell number, increased T cell proliferation, increased anti-double stranded DNA antibody level [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (17 sources): abnormal T cell activation, abnormal embryonic hematopoiesis, abnormal proerythroblast morphology, abnormal vascular endothelial cell development, abnormal vasculogenesis, absent visceral yolk sac blood islands, decreased body size, decreased regulatory T cell number, dermatitis, ear inflammation, [+]