Anxiety, Aspiration, Bowing of the vocal cords, Bulbar palsy, Bulbar signs, Decreased nerve conduction velocity, Degeneration of anterior horn cells, Dementia, Depression, Difficulty walking, Distal muscle weakness, Distal sensory impairment, Distal upper limb amyotrophy, Dysarthria, Dysphagia, Dyspnea, EMG abnormality, Elevated circulating creatine kinase concentration, Emotional lability, Exercise-induced myalgia, Fatigable weakness of bulbar muscles, Fatigable weakness of respiratory muscles, Fatigable weakness of swallowing muscles, Fatigue, Generalized muscle weakness, Hoarse voice, Hyperreflexia, Imperfect vocal cord adduction, Laryngospasm, Mildly elevated creatine kinase, Muscle spasm, Nasal speech, Nausea and vomiting, Neurodegeneration, Pain, Paralysis, Respiratory insufficiency, Respiratory insufficiency due to muscle weakness, Rimmed vacuoles, Shoulder girdle muscle weakness, Skeletal muscle atrophy, Spasticity, Unsteady gait, Vocal cord paresis, Weak voice, Xerostomia

embryonic lethality before implantation, incomplete penetrance, embryonic lethality between implantation and placentation, complete penetrance, impaired contextual conditioning behavior, impaired cued conditioning behavior, impaired righting response, increased microglial cell activation, limb grasping, neonatal lethality, complete penetrance, premature death, small cerebellum