nle1 Phenotypes

Phenotypes

XB-GENEPAGE-984058

Gene Symbol: nle1 Gene Name: notchless homolog 1

Anatomical Phenotypes Phenotypes manually curated with terms from the Xenopus phenotype ontology covering anatomical, gene ontology, and neurobehavioral phenotypes.
abnormally decreased number of Rohon-Beard neuron (1 source), absent Rohon-Beard neuron (1 source)

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Manual annotations: nle1 manipulated (1 source)

Experiments (Reagents) These are short form descriptions of experiments using reagents targeting the gene of interest.
Xla Wt + Mmu.Nle1 (1 source)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (19 sources): abnormal bone marrow cell morphology/development, abnormal cell morphology, abnormal common lymphocyte progenitor cell morphology, abnormal embryo development, abnormal hematopoietic stem cell physiology, abnormal immune system organ morphology, abnormal inner cell mass apoptosis, abnormal intestinal epithelium morphology, absent egg cylinders, decreased bone marrow cell number, decreased common myeloid progenitor cell number, decreased granulocyte number, decreased macrophage cell number, embryonic lethality between implantation and somite formation, complete penetrance, failure of blastocyst to hatch from the zona pellucida, hematopoietic system phenotype, immune system phenotype, impaired hematopoiesis, premature death [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (19 sources): abnormal bone marrow cell morphology/development, abnormal cell morphology, abnormal common lymphocyte progenitor cell morphology, abnormal embryo development, abnormal hematopoietic stem cell physiology, abnormal immune system organ morphology, abnormal inner cell mass apoptosis, abnormal intestinal epithelium morphology, absent egg cylinders, decreased bone marrow cell number, [+]