Abnormality of the vertebral column, Abnormality on pulmonary function testing, Amenorrhea, Astrocytoma, Ataxia, Back pain, Benign neoplasm of the central nervous system, Bilateral vestibular Schwannoma, Bitemporal hemianopia, Blindness, Brain stem compression, Cafe-au-lait spot, Cataract, Cerebral hemorrhage, Chromosomal breakage induced by ionizing radiation, Cognitive impairment, Corneal opacity, Cortical cataract, Cranial nerve paralysis, Decreased circulating ACTH level, Decreased circulating cortisol level, Decreased circulating follicle stimulating hormone concentration, Decreased circulating luteinizing hormone level, Decreased serum estradiol, Decreased serum testosterone concentration, Difficulty walking, Dysgraphia, Ear pain, Emotional lability, Enlarged pituitary gland, Ependymoma, Epiretinal membrane, Excessive daytime somnolence, Facial palsy, Focal T2 hypointense thalamic lesion, Focal-onset seizure, Functional motor deficit, Gait disturbance, Headache, Hearing impairment, Hemifacial spasm, Hemiparesis, Hydrocephalus, Hypogonadotropic hypogonadism, Hypothalamic hypothyroidism, Impotence, Increased circulating prolactin concentration, Increased intracranial pressure, Increased sensitivity to ionizing radiation, Intracranial meningioma, Juvenile posterior subcapsular lenticular opacities, Lower limb muscle weakness, Memory impairment, Meningioma, Migraine, Multiple cafe-au-lait spots, Nausea and vomiting, Neoplasm of the anterior pituitary, Neoplasm of the central nervous system, Neoplasm of the posterior pituitary, Neoplasm of the skin, Neoplasm of the tongue, Neurofibromas, Neurological speech impairment, Obesity, Occasional neurofibromas, Oculomotor nerve palsy, Ophthalmoplegia, Papilledema, Papule, Peripheral Schwannoma, Peripheral neuropathy, Pituitary hypothyroidism, Progressive pulmonary function impairment, Proptosis, Pseudoepiphyses of the metacarpals, Reduced circulating prolactin concentration, Retinal hamartoma, Schwannoma, Secondary growth hormone deficiency, Seizure, Sensorineural hearing impairment, Sensory neuropathy, Slow decrease in visual acuity, Spinal cord tumor, Spinal meningioma, Subcutaneous nodule, Syncope, Tinnitus, Transient global amnesia, Trigeminal neuralgia, Unilateral vestibular Schwannoma, Upper limb muscle weakness, Urinary incontinence, Vertigo, Visual acuity test abnormality, Visual impairment, Weak extraocular muscles

abnormal osteoblast morphology, abnormal placenta morphology, abnormal renal tubule morphology, abnormal spinal nerve morphology, abnormal tooth development, abnormal visceral endoderm morphology, absent extraembryonic ectoderm, absent mesoderm, circling, decreased body size, decreased survivor rate, disorganized extraembryonic tissue, embryonic lethality between implantation and somite formation, incomplete penetrance, embryonic lethality, complete penetrance, enlarged dorsal root ganglion, failure to gastrulate, head bobbing, head tilt, head tossing, impaired righting response, impaired swimming, increased Schwann cell number, increased Schwannoma incidence, increased extremity angiosarcoma incidence, increased fibroadenoma incidence, increased fibrosarcoma incidence, increased hamartoma incidence, increased hepatobiliary system tumor incidence, increased hepatocellular carcinoma incidence, increased lymphoma incidence, increased malignant tumor incidence, increased meningioma incidence, increased mesothelioma incidence, increased neurofibroma incidence, increased odontosarcoma incidence, increased or absent threshold for auditory brainstem response, increased osteoma incidence, increased pituitary adenoma incidence, increased renal carcinoma incidence, increased susceptibility to otitis media, increased thermal nociceptive threshold, increased tumor incidence, lethality throughout fetal growth and development, incomplete penetrance, nervous system phenotype, osseous metaplasia, perinatal lethality, incomplete penetrance, postnatal lethality, complete penetrance, postnatal lethality, incomplete penetrance, premature death, sensorineural hearing loss, small ectoplacental cone, trunk curl