Broad hallux, Broad thumb, Bulbous nose, Cardiomyopathy, Cataract, Cleft palate, Coarse facial features, Deep palmar crease, Deep plantar creases, Delayed eruption of teeth, Depressed nasal bridge, Downslanted palpebral fissures, Downturned corners of mouth, Epicanthus, Facial hypertrichosis, Flat forehead, Generalized hyperpigmentation, Generalized hypertrichosis, Generalized hypotonia, Gingival fibromatosis, Gingival overgrowth, Global developmental delay, Growth abnormality, Growth delay, Hallux valgus, Hearing impairment, Hepatomegaly, High palate, Hirsutism, Hyperextensibility of the finger joints, Hypertelorism, Hypodontia, Hypoplastic fingernail, Hypoplastic thumbnail, Hypotonia, Infantile muscular hypotonia, Intellectual disability, Intellectual disability, progressive, Intellectual disability, severe, Joint hypermobility, Large fleshy ears, Long eyelashes, Long penis, Long philtrum, Macroglossia, Mandibular prognathia, Micrognathia, Myopathic facies, Myopia, Nephrolithiasis, Overtubulated long bones, Patent ductus arteriosus, Pes cavus, Pes planus, Posteriorly rotated ears, Pseudoepiphysis of the thumb, Scoliosis, Seizure, Sensorineural hearing impairment, Short distal phalanx of finger, Short distal phalanx of toe, Short neck, Small nail, Soft skin, Spina bifida occulta, Splenomegaly, Supernumerary tooth, Synophrys, Telecanthus, Thick eyebrow, Thick lower lip vermilion, Thick nasal alae, Thick vermilion border, Thickened ears, Umbilical hernia, Wide mouth, Wide nasal bridge, Wide nose