f2r Phenotypes

Summary

Expression

Phenotypes

XB-GENEPAGE-985798

Gene Symbol: f2r Gene Name: coagulation factor 2 (thrombin) receptor

Expression Phenotypes Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: f2r assayed (2 sources)

Monarch Ortholog Phenotypes These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Mouse (43 sources): abnormal blood pressure regulation, abnormal bone volume, abnormal carotid artery morphology, abnormal cytokine level, abnormal fertility/fecundity, abnormal intestine physiology, abnormal neuron apoptosis, abnormal placenta development, abnormal response to cardiac infarction, abnormal sinus venosus morphology, abnormal systemic arterial blood pressure, abnormal systemic arterial blood pressure regulation, abnormal urine protein level, abnormal vascular wound healing, abnormal vitelline vasculature morphology, absent heartbeat, absent vitelline blood vessels, cardiovascular system phenotype, curly tail, decreased bone trabecular spacing, decreased embryo size, decreased sensitivity to induced morbidity/mortality, decreased survivor rate, decreased susceptibility to endotoxin shock, decreased susceptibility to induced colitis, decreased vascular permeability, dilated heart left ventricle, distended pericardium, embryonic growth retardation, embryonic lethality during organogenesis, incomplete penetrance, enlarged mesenteric lymph nodes, hematopoietic system phenotype, homeostasis/metabolism phenotype, immune system phenotype, increased bone trabecula number, increased compact bone volume, increased heart weight, increased trabecular bone volume, increased urine pH, increased urine sodium level, lethality throughout fetal growth and development, incomplete penetrance, long femur, skeleton phenotype [+]

Monarch Ortholog Phenotypes

These phenotypes are associated with this gene with a has phenotype relation via Monarch.

Mouse (43 sources): abnormal blood pressure regulation, abnormal bone volume, abnormal carotid artery morphology, abnormal cytokine level, abnormal fertility/fecundity, abnormal intestine physiology, abnormal neuron apoptosis, abnormal placenta development, abnormal response to cardiac infarction, abnormal sinus venosus morphology, [+]