| Monarch Ortholog Phenotypes
|
Human (62 sources):
Abnormal facial shape,
Abnormal foot morphology,
Abnormal heart morphology,
Abnormality of brain morphology,
Anteverted nares,
Arthrogryposis multiplex congenita,
Atrial septal defect,
Attention deficit hyperactivity disorder,
Auditory sensitivity,
Autism,
Autistic behavior,
Bilateral ptosis,
Brachycephaly,
Cerebral palsy,
Compulsive behaviors,
Congenital contracture,
Cryptorchidism,
Decreased palmar creases,
Delayed speech and language development,
Downslanted palpebral fissures,
Eczematoid dermatitis,
Epicanthus,
Feeding difficulties,
Feeding difficulties in infancy,
Generalized hypotonia,
Global developmental delay,
Highly arched eyebrow,
Hyperactivity,
Hyperreflexia,
Hypertelorism,
Intellectual disability,
Joint contracture of the 5th finger,
Joint contracture of the hand,
Kyphosis,
Low-set ears,
Microcephaly,
Micrognathia,
Motor stereotypy,
Narrow mouth,
Narrow palm,
Periauricular skin pits,
Prominent nasal tip,
Proptosis,
Ptosis,
Repetitive compulsive behavior,
Retrognathia,
Scoliosis,
Seizure,
Short palpebral fissure,
Short philtrum,
Short stature,
Small for gestational age,
Spasticity,
Specific learning disability,
Strabismus,
Thick eyebrow,
Thick vermilion border,
Umbilical hernia,
Upslanted palpebral fissure,
Wide mouth,
Wide nasal base,
Wide nasal bridge
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Mouse (26 sources):
abnormal Mullerian duct topology,
abnormal axon extension,
abnormal body length,
abnormal bone mineralization,
abnormal collateral sprouting,
abnormal ductus venosus valve morphology,
abnormal habituation to a new environment,
abnormal hypoglossal nerve topology,
abnormal long term object recognition memory,
absent segment of posterior cerebral artery,
behavior/neurological phenotype,
decreased anxiety-related response,
decreased body length,
decreased bone mineral content,
decreased exploration in new environment,
decreased food intake,
decreased vocalization,
embryo tumor,
impaired cued conditioning behavior,
impaired righting response,
increased bone mineral content,
increased lean body mass,
increased startle reflex,
neonatal lethality, complete penetrance,
positive geotaxis,
preweaning lethality, complete penetrance
[+]
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View all ortholog results at Monarch
|
Gene expression phenotype annotations where the gene of interest has been
disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from
differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1,
FDR <= 0.05 and an absolute LogFC >= 2.