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Summary Expression Phenotypes Gene Literature (0) GO Terms (5) Nucleotides (82) Proteins (25) Interactants (56) Wiki
XB-GENEPAGE-987848

iars2     isoleucyl-tRNA synthetase 2, mitochondrial

Expression Phenotypes
Gene expression phenotype annotations where the gene of interest has been disrupted (manipulated) or is the gene assayed (assayed). Computed annotations are derived from differential expression analysis from Xenbase processed GEO data with the criteria of a TPM >= 1, FDR <= 0.05 and an absolute LogFC >= 2.
Computed annotations: iars2 assayed (1 source)
Monarch Ortholog Phenotypes
These phenotypes are associated with this gene with a has phenotype relation via Monarch.
Human (56 sources): Abnormal vertebral morphology, Achalasia, Bilateral sensorineural hearing impairment, Brachydactyly, Cataract, Central adrenal insufficiency, Cerebral cortical atrophy, Cervical spinal canal stenosis, Congenital hip dislocation, Deeply set eye, [+]
Mouse (6 sources): abnormal embryo size, abnormal hematocrit, decreased startle reflex, embryonic lethality prior to organogenesis, prenatal lethality prior to heart atrial septation, preweaning lethality, complete penetrance

View all ortholog results at Monarch